The indirect Coombs test is used to determine if there are antibodies to the Rh factor in the mother’s blood. A blood sample is needed for this test and no special preparations are required.
A needle is inserted to draw blood. Some people feel moderate pain while others feel just a pricking or stinging.
What does the results of the Coombs test mean ?
A normal ( negative) results means that the mother has not developed any antibodies against the fetus blood. As a result the fetus is not in any danger from problems associated with Rh compatibility.
An abnormal ( positive ) result means the mother has developed antibodies to the fetal red blood cells and is sensitized. The test only indicates that an Rh positive fetus has the possibility of being harmed. It does not indicate the amount of harm that is likely to occur or that has already occurred.
If the test shows that antibody levels are rising during pregnancy, the fetus may be at greater risk of harm.
An Rh negative fetus will not be harmed even if the mother is sensitized.
Content Sources
Coombs Test. National Library of medicine. MedlinePlus. https://medlineplus.gov/ency/article/003344.htm. Accessed June 23rd, 2017
Indirect Coombs Test. Sutter Health. http://www.sutterhealth.org/health/healthinfo/index.php?A=C&hwid=hw139013. Accessed June 23rd, 2017