Hutchinson-Gilford Progeria Syndrome is commonly known as progeria or HGPS. It is a genetic disorder that manifests itself physically in children as rapid aging. The most common type of this condition is known as Hutchinson-Gilford Progeria Syndrome.
What are the symptoms of HGPS ?
Symptoms doesnt usually show until about 18 to 24 months old. These children are born looking healthy. Signs include the following :
- growth failure
- stiffness of joint
- aged looking skin
- hip dislocation
- loss of body fat and hair
- cardiovascular disease and stroke
- generalized atherosclerosis
This condition is fatal and usually results in death by heart disease around the age of 14. However life span can range between 18 and 21.
Who is at risk ?
Progeria doesnt occur because the mother or father has a genetic predisposition for the disorder. It is instead caused by a new mutation at the time of conception. As a result of this , the rate of progeria is spread fairly equal among both genders and ethnicities. There is no way to pass this disorder along since the mutation is spontaneous. However having a child with condition increases your risk of having another child with it by 2 to 3 %.
How is it diagnosed ?
HGPS can be tested for in an amniocentesis. However it is typically not tested for because its extremely rare and there is no genetic link.
Is there any treatment for children with progeria ?
Children with this condition can achieve a fair quality of life with the right care . Treatment may address physical issues associated with this condition .
Content Sources
Progeria. Mayo Foundation. http://www.mayoclinic.org/diseases-conditions/progeria/basics/definition/con-20029424. Accessed December 28, 2016
Progeria. WebMD. http://www.webmd.com/children/guide/progeria#1. Accessed December 28, 2016